Published Work

The Child-BEAR-Net CRC members have published a number of articles in leading journals. Child-BEAR-Net CRC is gaining a name as a leading voice in their area.

Guidelines

Chang AB, Zacharasiewicz A, Goyal V, Boyd J, Alexopoulou E, Aliberti S, Bell L, Bush A, Claydon A, Constant C, Fortescue R, Hill AT, Karadag B, Powell Z, Wilson C, Grimwood K, Kantar A; other members of Child-BEAR-Net; Chalmers J, Collaro A, Douros K, Griese M, Grigg J, Hector A, Mazulov O, Midulla F, Möller A, Proesmans M, Yerkovich S. European Respiratory Society statement for defining respiratory exacerbations in children and adolescents with bronchiectasis for clinical trials. Eur Respir J. 2022 Nov 3;60(5):2200300. doi: 10.1183/13993003.00300-2022. PMID: 35728974.

Chang AB, Fortescue R, Grimwood K, Alexopoulou E, Bell L, Boyd J, Bush A, Chalmers JD, Hill AT, Karadag B, Midulla F, McCallum GB, Powell Z, Snijders D, Song WJ, Tonia T, Wilson C, Zacharasiewicz A, Kantar A. Task Force report: European Respiratory Society guidelines for the management of children and adolescents with bronchiectasis. Eur Respir J. 2021 Feb 11:2002990. doi: 10.1183/13993003.02990-2020.

Randomised Clinical Trials

Goyal V, Grimwood K, Ware RS, Byrnes CA, Morris PS, Masters IB, McCallum GB, Binks MJ, Smith-Vaughan H, O'Grady KF, Champion A, Buntain HM, Schultz A, Chatfield M, Torzillo PJ, Chang AB. Efficacy of oral amoxicillin-clavulanate or azithromycin for non-severe respiratory exacerbations in children with bronchiectasis (BEST-1): a multicentre, three-arm, double-blind, randomised placebo-controlled trial. Lancet Respir Med. 2019 Sep;7(9):791-801. doi: 10.1016/S2213-2600(19)30254-1

Goyal V, Grimwood K, Byrnes CA, Morris PS, Masters IB, Ware RS, McCallum GB, Binks MJ, Marchant JM, van Asperen P, O'Grady KF, Champion A, Buntain HM, Petsky H, Torzillo PJ, Chang AB. Amoxicillin-clavulanate versus azithromycin for respiratory exacerbations in children with bronchiectasis (BEST-2): a multicentre, double-blind, non-inferiority, randomised controlled trial. Lancet. 2018 Oct 6;392(10154):1197-1206. doi: 10.1016/S0140-6736(18)31723-9

Reviews & Research Priorities

Chang AB, Boyd J, Bush A, Grimwood K, Hill AT, Powell Z, Yerkovich S, Zacharasiewicz A, Kantar A; network. Children's Bronchiectasis Education Advocacy and Research Network (Child-BEAR-Net): an ERS Clinical Research Collaboration on improving outcomes of children and adolescents with bronchiectasis. Eur Respir J. 2021 Oct 21;58(4):2101657. doi: 10.1183/13993003.01657-2021.

Chang AB, Boyd J, Bell L, et al. Clinical and research priorities for children and young people with bronchiectasis: an international roadmap. ERJ Open Res 2021; 7: 00122-2021 [DOI: 10.1183/23120541.00122-2021]

Chang AB, Bush A, Grimwood K. Bronchiectasis in children: Diagnosis and Treatment. Lancet 2018; 392:866-879

Other Recent Publications

Refining diagnostic criteria for paediatric bronchiectasis using low-dose CT scan

Factors associated with "Frequent Exacerbator" phenotype in children with bronchiectasis: The first report on children from the Australian Bronchiectasis Registry

Comparison of Profiles of First Nations and Non-First Nations Children With Bronchiectasis Over Two 5-Year Periods in the Northern Territory, Australia